openclinica CVE Vulnerabilities & Metrics

Focus on openclinica vulnerabilities and metrics.

Last updated: 03 Dec 2025, 23:25 UTC

About openclinica Security Exposure

This page consolidates all known Common Vulnerabilities and Exposures (CVEs) associated with openclinica. We track both calendar-based metrics (using fixed periods) and rolling metrics (using gliding windows) to give you a comprehensive view of security trends and risk evolution. Use these insights to assess risk and plan your patching strategy.

For a broader perspective on cybersecurity threats, explore the comprehensive list of CVEs by vendor and product. Stay updated on critical vulnerabilities affecting major software and hardware providers.

Global CVE Overview

Total openclinica CVEs: 4
Earliest CVE date: 14 May 2022, 00:15 UTC
Latest CVE date: 10 Nov 2025, 01:15 UTC

Latest CVE reference: CVE-2025-12922

Rolling Stats

30-day Count (Rolling): 2
365-day Count (Rolling): 2

Calendar-based Variation

Calendar-based Variation compares a fixed calendar period (e.g., this month versus the same month last year), while Rolling Growth Rate uses a continuous window (e.g., last 30 days versus the previous 30 days) to capture trends independent of calendar boundaries.

Variations & Growth

Month Variation (Calendar): 0%
Year Variation (Calendar): 0%

Month Growth Rate (30-day Rolling): 0.0%
Year Growth Rate (365-day Rolling): 0.0%

Monthly CVE Trends (current vs previous Year)

Annual CVE Trends (Last 20 Years)

Critical openclinica CVEs (CVSS ≥ 9) Over 20 Years

CVSS Stats

Average CVSS: 6.38

Max CVSS: 7.5

Critical CVEs (≥9): 0

CVSS Range vs. Count

Range Count
0.0-3.9 0
4.0-6.9 2
7.0-8.9 2
9.0-10.0 0

CVSS Distribution Chart

Top 5 Highest CVSS openclinica CVEs

These are the five CVEs with the highest CVSS scores for openclinica, sorted by severity first and recency.

All CVEs for openclinica

CVE-2025-12922 openclinica vulnerability CVSS: 6.5 10 Nov 2025, 01:15 UTC

A vulnerability was found in OpenClinica Community Edition up to 3.12.2/3.13. This affects an unknown part of the file /ImportCRFData?action=confirm of the component CRF Data Import. Performing manipulation of the argument xml_file results in path traversal. The attack can be initiated remotely. The exploit has been made public and could be used. The vendor was contacted early about this disclosure but did not respond in any way.

CVE-2025-12921 openclinica vulnerability CVSS: 4.0 10 Nov 2025, 00:15 UTC

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

CVE-2022-24831 openclinica vulnerability CVSS: 7.5 14 May 2022, 01:15 UTC

OpenClinica is an open source software for Electronic Data Capture (EDC) and Clinical Data Management (CDM). Versions prior to 3.16.1 are vulnerable to SQL injection due to the use of string concatenation to create SQL queries instead of prepared statements. No known workarounds exist. This issue has been patched in 3.16.1, 3.15.9, 3.14.1, and 3.13.1 and users are advised to upgrade.

CVE-2022-24830 openclinica vulnerability CVSS: 7.5 14 May 2022, 00:15 UTC

OpenClinica is an open source software for Electronic Data Capture (EDC) and Clinical Data Management (CDM). OpenClinica prior to version 3.16 is vulnerable to path traversal in multiple endpoints, leading to arbitrary file read/write, and potential remote code execution. There are no known workarounds. This issue has been patched and users are recommended to upgrade.