CVE-2025-12921 Vulnerability Analysis & Exploit Details

CVE-2025-12921
Vulnerability Scoring

4.3
/10
Medium Risk

The vulnerability CVE-2025-12921 could compromise system integrity but typically requires user interaction to be exploited.

Attack Complexity Details

  • Attack Complexity: Low
    Exploits can be performed without significant complexity or special conditions.
  • Attack Vector: Network
    Vulnerability is exploitable over a network without physical access.
  • Privileges Required: Low
    Some privileges are necessary to exploit the vulnerability.
  • Scope: Unchanged
    Exploit remains within the originally vulnerable component.
  • User Interaction: None
    No user interaction is necessary for exploitation.

CVE-2025-12921 Details

Status: Received on 10 Nov 2025, 00:15 UTC

Published on: 10 Nov 2025, 00:15 UTC

CVSS Release: version 3

CVSS3 Source

cna@vuldb.com

CVSS3 Type

Primary

CVSS3 Vector

CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N

CVE-2025-12921 Vulnerability Summary

CVE-2025-12921: A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

Assessing the Risk of CVE-2025-12921

Access Complexity Graph

The exploitability of CVE-2025-12921 depends on two key factors: attack complexity (the level of effort required to execute an exploit) and privileges required (the access level an attacker needs).

Exploitability Analysis for CVE-2025-12921

CVE-2025-12921 presents an accessible attack vector with minimal effort required. Restricting access controls and implementing security updates are critical to reducing exploitation risks.

Understanding AC and PR

A lower complexity and fewer privilege requirements make exploitation easier. Security teams should evaluate these aspects to determine the urgency of mitigation strategies, such as patch management and access control policies.

Attack Complexity (AC) measures the difficulty in executing an exploit. A high AC means that specific conditions must be met, making an attack more challenging, while a low AC means the vulnerability can be exploited with minimal effort.

Privileges Required (PR) determine the level of system access necessary for an attack. Vulnerabilities requiring no privileges are more accessible to attackers, whereas high privilege requirements limit exploitation to authorized users with elevated access.

CVSS Score Breakdown Chart

Above is the CVSS Sub-score Breakdown for CVE-2025-12921, illustrating how Base, Impact, and Exploitability factors combine to form the overall severity rating. A higher sub-score typically indicates a more severe or easier-to-exploit vulnerability.

CIA Impact Analysis

Below is the Impact Analysis for CVE-2025-12921, showing how Confidentiality, Integrity, and Availability might be affected if the vulnerability is exploited. Higher values usually signal greater potential damage.

  • Confidentiality: Low
    CVE-2025-12921 could lead to minor leaks of non-critical information without major privacy breaches.
  • Integrity: None
    CVE-2025-12921 poses no threat to data integrity.
  • Availability: None
    CVE-2025-12921 does not impact system availability.

CVE-2025-12921 References

External References

CWE Common Weakness Enumeration

CWE-91

CAPEC Common Attack Pattern Enumeration and Classification

  • XML Injection CAPEC-250 An attacker utilizes crafted XML user-controllable input to probe, attack, and inject data into the XML database, using techniques similar to SQL injection. The user-controllable input can allow for unauthorized viewing of data, bypassing authentication or the front-end application for direct XML database access, and possibly altering database information.
  • XPath Injection CAPEC-83 An attacker can craft special user-controllable input consisting of XPath expressions to inject the XML database and bypass authentication or glean information that they normally would not be able to. XPath Injection enables an attacker to talk directly to the XML database, thus bypassing the application completely. XPath Injection results from the failure of an application to properly sanitize input used as part of dynamic XPath expressions used to query an XML database.

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  • CVE-2025-12922 – A vulnerability was found in OpenClinica Community Edition up to 3.12.2/3.13. This affects an unknown part of the file /ImportCRFData?action=confir...
  • CVE-2025-12921 – A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file...